From 220 to 215 B.C. Kalymnos is subject to Kos which together with Rhodes and Rome, took part in the war against Phillip the 5th of Macedonia. (Not to be confused with FYROM or
Skopje which has usurped the name in recent times.) Rome is the up and coming power of that age and takes full advantage of the disputes between Alexander the Great's successors to further extend its supremacy.